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Sports injuries and strains due to overuse are the most common causes of muscle pain. Here we look at how to identify and treat muscle pain. When a muscle is injured, inflammation can cause pain and swelling. You may feel tenderness when the muscle is moved or touched. Suffering from muscle pain can be distressing and limit your ability to move freely. Muscle pain is most commonly the result of overuse or a minor injury, perhaps caused by a tough game of tennis or a trip or fall, or by tension and stress, which can make your muscles stiff and painful. Muscle pain, usually affecting a few muscles or a small part of your body, is often caused by overuse or minor injury, for example a strain or sprain resulting from overdoing it on your morning run. Trips or falls can also lead to strains and sprains that cause muscle pain.