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increase the side effects of this medicine and should be used cautiously. Diazepam on Wikipedia: allzone.eu Organisms Affected. Amitriptyline; Cimetidine; Midazolam and Diazepam Do not use phenobarbital in this cocktail, due to unwanted (mainly unpredictable) drug interactions with the amitriptyline. Also see the Wikipedia article for CYP2D6. Tricyclic. The effects of long-term benzodiazepine use include drug dependence as well as the While benzodiazepines are highly effective in the short term, adverse effects in some people . Diazepam and clonazepam have been found to have long-lasting, but not permanent, immunotoxic effects in the fetus of pregnant rats.

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