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Feb 19, - Keywords: Diazepam, Valium, benzodiazepine, GABA, anxiety, hypnotic, sedative profile, in contrast to the narrow therapeutic range of sedatives and hypnotics. . Drug half-life and free fraction increases in aged populations due to . In treatment of status epilepticus, 5–10 mg IV/IM every 10–15 min. Apr 17, - In patients with cirrhosis, a 2- to 5-fold increase in mean half-life has been .. Intravenous but not oral metoclopramide increases the rate of absorption of diazepam .. In contrast, this drug was shown to be non teratogenic at. In cats, diazepam has been administered IV for short-term stimulation of appetite. In cats Because of the short half-life of diazepam in dogs ( hours) and the . In contrast to diazepam, midazolam is water soluble and is well absorbed after.

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